Microbicides 2004 Microbicides 200428-31 March 2004, Hilton London MetropoleThe conference42 million men, women and children worldwide were living with HIV by the end of December 2002 (source: UNAIDS), including five million newly-infected during that year alone. Another 45 million people will become infected between 2002 and 2010, unless the current transmission rates can be vastly reduced. Of the 42 million, 29.4 million live in sub-Saharan Africa and 58% of them are women. Not only are women more susceptible to HIV infection, many are powerless to insist on the use of condoms or other methods of protecting themselves. In this context, and with the knowledge that an effective HIV vaccine is unlikely to be available for several years, the need for an effective topical microbicide grows ever more urgent. 2004 should prove to be a landmark year in the field of microbicide development as the first Phase III trials of novel products are due to start – the next step along the road to making a microbicide available to the millions worldwide in desperate need of protection.The aims of the Microbicides 2004 conference are to:Report novel or innovative work in the microbicides fieldProvide updates on recent microbicides research, divided into three tracks: basic science, clinical science, and behavioural science (including public health and the microbicide marketplace)Provide a forum for the discussion of new developments in microbicide research including ethical, clinical, behavioural and methodological issuesPresent opportunities for knowledge-sharing between microbicide researchers, public-health workers and advocacy organisations.There will be an opening ceremony on the evening of Sunday 28 March at which politicians, policy makers and the international media are expected. The conference will run for a full three days, each of which will contain:Scientific overviews and presentations with plenary sessions, invited lecturers and presentations of original researchWorkshops to review issues unique to microbicides such as trial design and outcome measures, and ethical issues in the clinical trials of microbicidesPoster sessions. Focus on LondonFollowing the successful Microbicides conferences in Washington in 2000 and Antwerp in 2002, March 2004 sees the focus move to London.The venue is the Hilton Metropole Hotel, two minutes by taxi from Paddington station and the Heathrow Express, with a journey time from the airport of 15 minutes. The hotel is in walking distance of Hyde Park and London’s main shopping streets, and close to Imperial College. Accommodation will be available at the venue and other hotels in the vicinity.London in March offers a variety of diversions for out-of-conference relaxation, including sight-seeing and shopping; the arts and the theatre; and pubs, clubs and restaurants to suit every taste. Conference staff will be on hand to help delegates plan their spare time.To book your place or find out more information, e-mail info@microbicides2004.org.uk or telephone the Event Office on +44 (0) 20 7720 4411
Oral: invited speaker Oral: Track A Oral: Track B Oral: Track C Poster: Track A Poster: Track B Poster: Track C Abstract only Authors

02528 ACCEPTABILITY OF A VAGINAL GEL AS A PROTECTIVE BARRIER AGAINST STDS AND HIV IN ADOLESCENT GIRLS AND SEX WORKERS IN DAKAR

Marie Cisse Thioye
Center STD/HIV/AIDS Dakar Senegal

Introduction: The STI center in Polyclinique of Dakar deals with nearly more 1000 sex-workers. In Senegal, the practice of prostitution has been tolerated since 1962 (Decree No 62036 dated 13 August 1962).

Objective: To evaluate the level of knowledge and acceptance of microbicides among authorized prostitutes and now for adolescent girls (50 adolescent girls sex workers are informed of microbicides). To warn against HIV infection and the STI. To inform prostitutes about the use, the effects and the signification of microbicides.

Methodology: In the Institut d’Hygiene Social site, selection of 300 prostitutes living with or no without the HIV and registered for the sanitary index, 50 adolescent girls sex workers; information is obtained from prostitutes through interviews based on a questionnaire about the knowledge and acceptance of ways of using preventive methods against the transmission of HIV, in particular (male condoms, female condoms or femidon, microbicides).

Result: About the knowledge of microbicides
300 prostitutes and 50 adolescent girls are sensibilized
14% have heard of microbicides
98% have accepted to be part of a study on microbicides mainly those who have fixed partners
1% have regained doing so.

Conclusion: The study in process sex workers need protection since they constitute a risk group. This microbicide can play a very important role in the prevention of STI/HIV/AIDS. The use of microbicides is an alternative method particularly with partners refusing to use male condoms. I think also the only alternative methods of prevention, which can be controlled by women, has led to interest in the development of microbicide.

Marie Cisse Thioye
Tel 221 641 65 12 Fax 821 02 83, Rue 1 x Blaise Diagne Polyclinique